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Insights into the G-rich VEGF-binding aptamer V7t1: when two G-quadruplexes are better than one!
The G-quadruplex-forming VEGF-binding aptamer V7t1 was previously found to be highly polymorphic in a K(+)-containing solution and, to restrict its conformational preferences to a unique, well-defined form, modified nucleotides (LNA and/or UNA) were inserted in its sequence. We here report an in-dep...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735921/ https://www.ncbi.nlm.nih.gov/pubmed/31276595 http://dx.doi.org/10.1093/nar/gkz589 |