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Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer
MicroRNAs (miRNAs) are short, noncoding RNAs that regulate gene expression by suppressing mRNA translation and reducing mRNA stability. A miRNA can potentially bind many mRNAs, thereby affecting the expression of oncogenes and tumor suppressor genes as well as the activity of whole pathways. The pro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735922/ https://www.ncbi.nlm.nih.gov/pubmed/31340025 http://dx.doi.org/10.1093/nar/gkz638 |