Anti-αFR CAR-engineered NK-92 Cells Display Potent Cytotoxicity Against αFR-positive Ovarian Cancer

Folate receptor alpha (αFR) is overexpressed in 90% of ovarian cancers, one of the most lethal gynecologic cancers. Recent studies have suggested that natural killer (NK) cells may be better chimeric antigen receptor (CAR) drivers because of their favorable innate characteristics, such as directly r...

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Detalles Bibliográficos
Autores principales: Ao, Xiang, Yang, Yu, Li, Weiqiang, Tan, Yan, Guo, Wei, Ao, Luoquan, He, Xiao, Wu, Xiaofeng, Xia, Jianchuan, Xu, Xiang, Guo, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Basic Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735933/
https://www.ncbi.nlm.nih.gov/pubmed/31261167
http://dx.doi.org/10.1097/CJI.0000000000000286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735933/
https://www.ncbi.nlm.nih.gov/pubmed/31261167
http://dx.doi.org/10.1097/CJI.0000000000000286

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