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Anti-αFR CAR-engineered NK-92 Cells Display Potent Cytotoxicity Against αFR-positive Ovarian Cancer
Folate receptor alpha (αFR) is overexpressed in 90% of ovarian cancers, one of the most lethal gynecologic cancers. Recent studies have suggested that natural killer (NK) cells may be better chimeric antigen receptor (CAR) drivers because of their favorable innate characteristics, such as directly r...
Autores principales: | Ao, Xiang, Yang, Yu, Li, Weiqiang, Tan, Yan, Guo, Wei, Ao, Luoquan, He, Xiao, Wu, Xiaofeng, Xia, Jianchuan, Xu, Xiang, Guo, Jianxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735933/ https://www.ncbi.nlm.nih.gov/pubmed/31261167 http://dx.doi.org/10.1097/CJI.0000000000000286 |
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