Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes

eIF3 is a large multiprotein complex serving as an essential scaffold promoting binding of other eIFs to the 40S subunit, where it coordinates their actions during translation initiation. Perhaps due to a high degree of flexibility of multiple eIF3 subunits, a high-resolution structure of free eIF3...

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Detalles Bibliográficos
Autores principales: Zeman, Jakub, Itoh, Yuzuru, Kukačka, Zdeněk, Rosůlek, Michal, Kavan, Daniel, Kouba, Tomáš, Jansen, Myrte E, Mohammad, Mahabub P, Novák, Petr, Valášek, Leoš S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735954/
https://www.ncbi.nlm.nih.gov/pubmed/31291455
http://dx.doi.org/10.1093/nar/gkz570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735954/
https://www.ncbi.nlm.nih.gov/pubmed/31291455
http://dx.doi.org/10.1093/nar/gkz570

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