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Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives

BACKGROUND: Antibodies to the blood stages of malaria parasites enhance parasite clearance and antimalarial efficacy. The antibody subclass and functions that contribute to parasite clearance during antimalarial treatment and their relationship to malaria transmission intensity have not been charact...

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Detalles Bibliográficos
Autores principales: O’Flaherty, Katherine, Ataíde, Ricardo, Zaloumis, Sophie G, Ashley, Elizabeth A, Powell, Rosanna, Feng, Gaoqian, Reiling, Linda, Dondorp, Arjen M, Day, Nicholas P, Dhorda, Mehul, Fairhurst, Rick M, Lim, Pharath, Amaratunga, Chanaki, Pukrittayakamee, Sasithon, Hien, Tran Tinh, Htut, Ye, Mayxay, Mayfong, Faiz, M Abul, Beeson, James G, Nosten, Francois, Simpson, Julie A, White, Nicholas J, Fowkes, Freya J I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735958/
https://www.ncbi.nlm.nih.gov/pubmed/31075171
http://dx.doi.org/10.1093/infdis/jiz247