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Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis
Chronic active and slowly expanding lesions with smouldering inflammation are neuropathological correlates of progressive multiple sclerosis pathology. T(1) hypointense volume and signal intensity on T(1)-weighted MRI reflect brain tissue damage that may develop within newly formed acute focal infla...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736181/ https://www.ncbi.nlm.nih.gov/pubmed/31497864 http://dx.doi.org/10.1093/brain/awz212 |