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Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas

Recurrent tumors originate from cancer stem cells (CSCs) that survive conventional treatments. CSCs consist of heterogeneous subpopulations that display distinct sensitivity to anticancer drugs. Such a heterogeneity presents a significant challenge in preventing tumor recurrence. In the current stud...

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Detalles Bibliográficos
Autores principales: Gao, WenChao, Xu, YuTing, Chen, Tao, Du, ZunGuo, Liu, XiuJuan, Hu, ZhiQian, Wei, Dong, Gao, ChunFang, Zhang, Wei, Li, QingQuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736310/
https://www.ncbi.nlm.nih.gov/pubmed/31461438
http://dx.doi.org/10.1371/journal.pbio.3000425