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Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas
Recurrent tumors originate from cancer stem cells (CSCs) that survive conventional treatments. CSCs consist of heterogeneous subpopulations that display distinct sensitivity to anticancer drugs. Such a heterogeneity presents a significant challenge in preventing tumor recurrence. In the current stud...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736310/ https://www.ncbi.nlm.nih.gov/pubmed/31461438 http://dx.doi.org/10.1371/journal.pbio.3000425 |