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A Sir2-regulated locus control region in the recombination enhancer of Saccharomyces cerevisiae specifies chromosome III structure

The NAD(+)-dependent histone deacetylase Sir2 was originally identified in Saccharomyces cerevisiae as a silencing factor for HML and HMR, the heterochromatic cassettes utilized as donor templates during mating-type switching. MATa cells preferentially switch to MATα using HML as the donor, which is...

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Detalles Bibliográficos
Autores principales: Li, Mingguang, Fine, Ryan D., Dinda, Manikarna, Bekiranov, Stefan, Smith, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736312/
https://www.ncbi.nlm.nih.gov/pubmed/31461456
http://dx.doi.org/10.1371/journal.pgen.1008339