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Progesterone Application to the Rat Forehead Produces Corneal Antinociception

PURPOSE: Ocular pain and discomfort are the most defining symptoms of dry eye disease. We determined the ability of topical progesterone to affect corneal sensitivity and brainstem processing of nociceptive inputs. METHODS: Progesterone or vehicle gel was applied to the shaved forehead in male Sprag...

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Detalles Bibliográficos
Autores principales: Meng, Ian D., Barton, Stephen T., Goodney, Ian, Russell, Rachel, Mecum, Neal E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736375/
https://www.ncbi.nlm.nih.gov/pubmed/31013343
http://dx.doi.org/10.1167/iovs.18-26049