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Shared Signature Dynamics Tempered by Local Fluctuations Enables Fold Adaptability and Specificity
Recent studies have drawn attention to the evolution of protein dynamics, in addition to sequence and structure, based on the premise structure-encodes-dynamics-encodes-function. Of interest is to understand how functional differentiation is accomplished while maintaining the fold, or how intrinsic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736388/ https://www.ncbi.nlm.nih.gov/pubmed/31028708 http://dx.doi.org/10.1093/molbev/msz102 |