Probing Metal Ion Discrimination in a Protein Designed to Bind Uranyl Cation With Femtomolar Affinity

The design of metal-binding sites in proteins that combine high affinity with high selectivity for the desired metal ion remains a challenging goal. Recently, a protein designed to display femtomolar affinity for [Formula: see text] , dubbed “Super Uranyl-binding Protein” (SUP), was described, with...

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Detalles Bibliográficos
Autores principales: Hoarau, Marie, Koebke, Karl J., Chen, Zhan, Marsh, E. Neil G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736553/
https://www.ncbi.nlm.nih.gov/pubmed/31552264
http://dx.doi.org/10.3389/fmolb.2019.00073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736553/
https://www.ncbi.nlm.nih.gov/pubmed/31552264
http://dx.doi.org/10.3389/fmolb.2019.00073

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