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Probing Metal Ion Discrimination in a Protein Designed to Bind Uranyl Cation With Femtomolar Affinity
The design of metal-binding sites in proteins that combine high affinity with high selectivity for the desired metal ion remains a challenging goal. Recently, a protein designed to display femtomolar affinity for [Formula: see text] , dubbed “Super Uranyl-binding Protein” (SUP), was described, with...
Autores principales: | Hoarau, Marie, Koebke, Karl J., Chen, Zhan, Marsh, E. Neil G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736553/ https://www.ncbi.nlm.nih.gov/pubmed/31552264 http://dx.doi.org/10.3389/fmolb.2019.00073 |
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