Inhibition of Cdk8/Cdk19 Activity Promotes Treg Cell Differentiation and Suppresses Autoimmune Diseases

Foxp3 expressing regulatory T (Treg) cells, as the central negative regulator of adaptive immune system, are essential to suppress immune response and maintain immune homeostasis. However, the function of Treg cells is frequently compromised in autoimmunity and hyper-activated in infections and tumo...

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Detalles Bibliográficos
Autores principales: Guo, Zengli, Wang, Gang, Lv, Yanfang, Wan, Yisong Y., Zheng, Junnian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736578/
https://www.ncbi.nlm.nih.gov/pubmed/31552016
http://dx.doi.org/10.3389/fimmu.2019.01988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736578/
https://www.ncbi.nlm.nih.gov/pubmed/31552016
http://dx.doi.org/10.3389/fimmu.2019.01988

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