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Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases

Sigma-1 receptor (S1R) is a multi-functional, ligand-operated protein situated in endoplasmic reticulum (ER) membranes and changes in its function and/or expression have been associated with various neurological disorders including amyotrophic lateral sclerosis/frontotemporal dementia, Alzheimer’s (...

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Detalles Bibliográficos
Autores principales: Ryskamp, Daniel A., Korban, Svetlana, Zhemkov, Vladimir, Kraskovskaya, Nina, Bezprozvanny, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736580/
https://www.ncbi.nlm.nih.gov/pubmed/31551669
http://dx.doi.org/10.3389/fnins.2019.00862