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FAT1, a direct transcriptional target of E2F1, suppresses cell proliferation, migration and invasion in esophageal squamous cell carcinoma

OBJECTIVE: Growing evidence indicates that FAT atypical cadherin 1 (FAT1) has aberrant genetic alterations and exhibits potential tumor suppressive function in esophageal squamous cell carcinoma (ESCC). However, the role of FAT1 in ESCC tumorigenesis remains not well elucidated. The aim of this stud...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Wang, Guangchao, Ma, Yunping, Teng, Jinglei, Wang, Yan, Cui, Yongping, Dong, Yan, Shao, Shujuan, Zhan, Qimin, Liu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736659/
https://www.ncbi.nlm.nih.gov/pubmed/31564804
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.04.05