Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories

Cardiosphere-derived cells (CDCs) are therapeutic candidates with disease-modifying bioactivity, but their variable potency has complicated their clinical translation. Transcriptomic analyses of CDCs from human donors have revealed that the therapeutic potency of these cells correlates with Wnt/β-ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Ibrahim, Ahmed G.E., Li, Chang, Rogers, Russel, Fournier, Mario, Li, Liang, Vaturi, Sharon D., Antes, Travis, Sanchez, Lizbeth, Akhmerov, Akbarshakh, Moseley, Jennifer Johnson, Tobin, Brooke, Rodriguez-Borlado, Luis, Smith, Rachel R., Marbán, Linda, Marbán, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736698/
https://www.ncbi.nlm.nih.gov/pubmed/31451800
http://dx.doi.org/10.1038/s41551-019-0448-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736698/
https://www.ncbi.nlm.nih.gov/pubmed/31451800
http://dx.doi.org/10.1038/s41551-019-0448-6

Ejemplares similares