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Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories
Cardiosphere-derived cells (CDCs) are therapeutic candidates with disease-modifying bioactivity, but their variable potency has complicated their clinical translation. Transcriptomic analyses of CDCs from human donors have revealed that the therapeutic potency of these cells correlates with Wnt/β-ca...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736698/ https://www.ncbi.nlm.nih.gov/pubmed/31451800 http://dx.doi.org/10.1038/s41551-019-0448-6 |