Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy

Metformin is the first-line therapy for treating type 2 diabetes and a promising anti-aging drug. We set out to address the fundamental question of how gut microbes and nutrition, key regulators of host physiology, affect the effects of metformin. Combining two tractable genetic models, the bacteriu...

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Detalles Bibliográficos
Autores principales: Pryor, Rosina, Norvaisas, Povilas, Marinos, Georgios, Best, Lena, Thingholm, Louise B., Quintaneiro, Leonor M., De Haes, Wouter, Esser, Daniela, Waschina, Silvio, Lujan, Celia, Smith, Reuben L., Scott, Timothy A., Martinez-Martinez, Daniel, Woodward, Orla, Bryson, Kevin, Laudes, Matthias, Lieb, Wolfgang, Houtkooper, Riekelt H., Franke, Andre, Temmerman, Liesbet, Bjedov, Ivana, Cochemé, Helena M., Kaleta, Christoph, Cabreiro, Filipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736778/
https://www.ncbi.nlm.nih.gov/pubmed/31474368
http://dx.doi.org/10.1016/j.cell.2019.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736778/
https://www.ncbi.nlm.nih.gov/pubmed/31474368
http://dx.doi.org/10.1016/j.cell.2019.08.003

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