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3D cell culture stimulates the secretion of in vivo like extracellular vesicles

For studying cellular communications ex-vivo, a two-dimensional (2D) cell culture model is currently used as the “gold standard”. 2D culture models are also widely used in the study of RNA expression profiles from tumor cells secreted extracellular vesicles (EVs) for tumor biomarker discovery. Altho...

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Detalles Bibliográficos
Autores principales: Thippabhotla, Sirisha, Zhong, Cuncong, He, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736862/
https://www.ncbi.nlm.nih.gov/pubmed/31506601
http://dx.doi.org/10.1038/s41598-019-49671-3