The double inhibition of PDK1 and STAT3-Y705 prevents liver metastasis in colorectal cancer

As a key glycolysis enzyme, the significance of pyruvate dehydrogenase kinase 1 (PDK1) in the development of colorectal cancer (CRC) remains unknown. This study revealed that the prognosis of CRC patients with high levels of PDK1 was poor, and PDK1 knockdown significantly reduced liver metastasis of...

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Detalles Bibliográficos
Autores principales: Qin, Wenjuan, Tian, Yun, Zhang, Jing, Liu, Wenjian, Zhou, Qiming, Hu, Sheng, Yang, Fei, Lu, Li, Lu, Haijie, Cui, Shuzhong, Wen, Lu, Wei, Shaozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736869/
https://www.ncbi.nlm.nih.gov/pubmed/31506552
http://dx.doi.org/10.1038/s41598-019-49480-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736869/
https://www.ncbi.nlm.nih.gov/pubmed/31506552
http://dx.doi.org/10.1038/s41598-019-49480-8

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