Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition

Polyphenols represent the most studied class of nutraceuticals that can be therapeutics for a large spectrum of diseases, including cancer. In this study, we investigated for the first time the antitumor activities of polyphenol extract from Annurca apple (APE) in MDA-MB-231 triple negative breast c...

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Detalles Bibliográficos
Autores principales: Martino, Elisa, Vuoso, Daniela Cristina, D’Angelo, Stefania, Mele, Luigi, D’Onofrio, Nunzia, Porcelli, Marina, Cacciapuoti, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736874/
https://www.ncbi.nlm.nih.gov/pubmed/31506575
http://dx.doi.org/10.1038/s41598-019-49631-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736874/
https://www.ncbi.nlm.nih.gov/pubmed/31506575
http://dx.doi.org/10.1038/s41598-019-49631-x

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