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Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition
Polyphenols represent the most studied class of nutraceuticals that can be therapeutics for a large spectrum of diseases, including cancer. In this study, we investigated for the first time the antitumor activities of polyphenol extract from Annurca apple (APE) in MDA-MB-231 triple negative breast c...
Autores principales: | Martino, Elisa, Vuoso, Daniela Cristina, D’Angelo, Stefania, Mele, Luigi, D’Onofrio, Nunzia, Porcelli, Marina, Cacciapuoti, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736874/ https://www.ncbi.nlm.nih.gov/pubmed/31506575 http://dx.doi.org/10.1038/s41598-019-49631-x |
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