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Transgenerational Self-Reconstruction of Disrupted Chromatin Organization After Exposure To An Environmental Stressor in Mice

Exposure to environmental stressors is known to increase disease susceptibility in unexposed descendants in the absence of detectable genetic mutations. The mechanisms mediating environmentally-induced transgenerational disease susceptibility are poorly understood. We showed that great-great-grandso...

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Detalles Bibliográficos
Autores principales: Diaz-Castillo, Carlos, Chamorro-Garcia, Raquel, Shioda, Toshi, Blumberg, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736928/
https://www.ncbi.nlm.nih.gov/pubmed/31506492
http://dx.doi.org/10.1038/s41598-019-49440-2