Cargando…

miRNA-dependent regulation of STIM1 expression in breast cancer

Store-operated Ca(2+) entry (SOCE) has been shown to be important for breast cancer metastasis in xenograft mouse models. The ER Ca(2+) sensor STIM1 and Orai plasma membrane Ca(2+) channels molecularly mediate SOCE. Here we investigate the role of the microRNA machinery in regulating STIM1 expressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulkarni, Rashmi P., Elmi, Asha, Alcantara-Adap, Ethel, Hubrack, Satanay, Nader, Nancy, Yu, Fang, Dib, Maya, Ramachandran, Vimal, Najafi Shoushtari, Hani, Machaca, Khaled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736934/
https://www.ncbi.nlm.nih.gov/pubmed/31506588
http://dx.doi.org/10.1038/s41598-019-49629-5