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Mathematical modeling for bioprocess optimization of a protein drug, uricase, production by Aspergillus welwitschiae strain 1–4

Microbial uricase is effective protein drug used to treat hyperuricemia and its complications, including chronic gout, also in prophylaxis and treatment of tumor lysis and organ transplants hyperuricemia. Uricase is commonly used as diagnostic reagent in clinical analysis for quantification of uric...

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Detalles Bibliográficos
Autores principales: El-Naggar, Noura El-Ahmady, Haroun, S. A., El-Weshy, Eman M., Metwally, E. A., Sherief, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736946/
https://www.ncbi.nlm.nih.gov/pubmed/31506445
http://dx.doi.org/10.1038/s41598-019-49201-1