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ATF6 regulates the development of chronic pancreatitis by inducing p53-mediated apoptosis

Chronic pancreatitis (CP) is a progressive, recurrent inflammatory disorder of the pancreas. Initiation and progression of CP can result from serine protease 1 (PRSS1) overaccumulation and the ensuing endoplasmic reticulum (ER) stress. However, how ER stress pathways regulate the development and pro...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Tan, Jie-hui, Cao, Rong-chang, Xu, Jia, Chen, Xue-mei, Qi, Zhao-chang, Zhou, Su-ying, Li, Su-bing, Mo, Qi-xin, Li, Zhi-wei, Zhang, Guo-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737032/
https://www.ncbi.nlm.nih.gov/pubmed/31506423
http://dx.doi.org/10.1038/s41419-019-1919-0