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MARK4 protein can explore the active-like conformations in its non-phosphorylated state

Microtubule affinity-regulating kinase 4 (MARK4) is a Ser/Thr protein kinase, best known for its role in phosphorylating microtubule associated proteins, causing their detachment from microtubules. In the current study, the non-phosphorylated conformation of the activation loop was modeled in a stru...

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Detalles Bibliográficos
Autores principales: Ahrari, Sajjad, Khosravi, Fatemeh, Osouli, Ali, Sakhteman, Amirhossein, Nematollahi, Alireza, Ghasemi, Younes, Savardashtaki, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737064/
https://www.ncbi.nlm.nih.gov/pubmed/31506531
http://dx.doi.org/10.1038/s41598-019-49337-0