Patched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1(+/−)/ODC transgenic mice

The study of dominantly heritable cancers has provided insights about tumor development. Gorlin syndrome (GS) is an autosomal dominant disorder wherein affected individuals develop multiple basal cell carcinomas (BCCs) of the skin. We developed a murine model of Ptch1 haploinsufficiency on an ornith...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Changzhao, Mishra, Bharat, Kashyap, Mahendra, Weng, Zhiping, Andrabi, Shaida A., Mukhtar, Shahid M., Kim, Arianna L., Bickers, David R., Kopelovich, Levy, Athar, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737076/
https://www.ncbi.nlm.nih.gov/pubmed/31506465
http://dx.doi.org/10.1038/s41598-019-49470-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737076/
https://www.ncbi.nlm.nih.gov/pubmed/31506465
http://dx.doi.org/10.1038/s41598-019-49470-w

Ejemplares similares