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Valproic Acid Enhances Reprogramming Efficiency and Neuronal Differentiation on Small Molecules Staged-Induction Neural Stem Cells: Suggested Role of mTOR Signaling

Inducing somatic cells into neural stem cells (iNSCs) in specific ways provides a new cell therapy in a variety of neurological diseases. In the past, iNSCs were generated by transcription factors which increased the risk of mutagenesis, tumor formations, and immune reactions by viral transduction v...

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Detalles Bibliográficos
Autores principales: Duan, Qingrui, Li, Siyi, Wen, Xinrui, Sunnassee, Gavin, Chen, Jian, Tan, Sheng, Guo, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737087/
https://www.ncbi.nlm.nih.gov/pubmed/31551670
http://dx.doi.org/10.3389/fnins.2019.00867