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Valproic Acid Enhances Reprogramming Efficiency and Neuronal Differentiation on Small Molecules Staged-Induction Neural Stem Cells: Suggested Role of mTOR Signaling
Inducing somatic cells into neural stem cells (iNSCs) in specific ways provides a new cell therapy in a variety of neurological diseases. In the past, iNSCs were generated by transcription factors which increased the risk of mutagenesis, tumor formations, and immune reactions by viral transduction v...
Autores principales: | Duan, Qingrui, Li, Siyi, Wen, Xinrui, Sunnassee, Gavin, Chen, Jian, Tan, Sheng, Guo, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737087/ https://www.ncbi.nlm.nih.gov/pubmed/31551670 http://dx.doi.org/10.3389/fnins.2019.00867 |
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