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Heteroplasmy concordance between mitochondrial DNA and RNA
Mitochondrial DNA (mtDNA) heteroplasmies are associated with various diseases but the transmission of heteroplasmy from mtDNA to mitochondrial RNA (mtRNA) remains unclear. We compared heteroplasmies in mtRNA from 446 human B-lymphoblastoid cell lines to their corresponding mtDNA using deep sequencin...
Autores principales: | Zhang, Ruoyu, Nakahira, Kiichi, Choi, Augustine M. K., Gu, Zhenglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737107/ https://www.ncbi.nlm.nih.gov/pubmed/31506522 http://dx.doi.org/10.1038/s41598-019-49279-7 |
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