Identification of a Kavain Analog with Efficient Anti-inflammatory Effects

Kavain, a compound derived from Piper methysticum, has demonstrated anti-inflammatory properties. To optimize its drug properties, identification and development of new kavain-derived compounds was undertaken. A focused library of analogs was synthesized and their effects on Porphyromonas gingivalis...

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Detalles Bibliográficos
Autores principales: Huck, Olivier, Han, Xiaxian, Mulhall, Hannah, Gumenchuk, Iryna, Cai, Bin, Panek, James, Iyer, Radha, Amar, Salomon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737110/
https://www.ncbi.nlm.nih.gov/pubmed/31506483
http://dx.doi.org/10.1038/s41598-019-49383-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737110/
https://www.ncbi.nlm.nih.gov/pubmed/31506483
http://dx.doi.org/10.1038/s41598-019-49383-8

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