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Identification of a Kavain Analog with Efficient Anti-inflammatory Effects
Kavain, a compound derived from Piper methysticum, has demonstrated anti-inflammatory properties. To optimize its drug properties, identification and development of new kavain-derived compounds was undertaken. A focused library of analogs was synthesized and their effects on Porphyromonas gingivalis...
Autores principales: | Huck, Olivier, Han, Xiaxian, Mulhall, Hannah, Gumenchuk, Iryna, Cai, Bin, Panek, James, Iyer, Radha, Amar, Salomon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737110/ https://www.ncbi.nlm.nih.gov/pubmed/31506483 http://dx.doi.org/10.1038/s41598-019-49383-8 |
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