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TIMAP inhibits endothelial myosin light chain phosphatase by competing with MYPT1 for the catalytic protein phosphatase 1 subunit PP1cβ

Transforming growth factor-β membrane associated protein (TIMAP) is an endothelial cell (EC)–predominant PP1 regulatory subunit and a member of the myosin phosphatase target (MYPT) protein family. The MYPTs preferentially bind the catalytic protein phosphatase 1 subunit PP1cβ, forming myosin phospha...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Obeidat, Marya, Li, Laiji, Pasarj, Phuwadet, Aburahess, Salah, Holmes, Charles F. B., Ballermann, Barbara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737228/
https://www.ncbi.nlm.nih.gov/pubmed/31315927
http://dx.doi.org/10.1074/jbc.RA118.006075