Cathelicidin Peptides Restrict Bacterial Growth via Membrane Perturbation and Induction of Reactive Oxygen Species

All metazoans produce antimicrobial peptides (AMPs) that have both broad antimicrobial and immunomodulatory activity. Cathelicidins are AMPs that preferentially kill Gram-negative bacteria in vitro, purportedly by assembling into higher-order structures that perforate the membrane. We utilized high-...

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Detalles Bibliográficos
Autores principales: Rowe-Magnus, Dean A., Kao, Adenine Y., Prieto, Antonio Cembellin, Pu, Meng, Kao, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737244/
https://www.ncbi.nlm.nih.gov/pubmed/31506312
http://dx.doi.org/10.1128/mBio.02021-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737244/
https://www.ncbi.nlm.nih.gov/pubmed/31506312
http://dx.doi.org/10.1128/mBio.02021-19

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