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Prader–Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT(2C)R-mediated response inhibition
Prader–Willi syndrome (PWS) is a neurodevelopmental disorder caused by deletion or inactivation of paternally expressed imprinted genes on human chromosome 15q11–q13. In addition to endocrine and developmental issues, PWS presents with behavioural problems including stereotyped behaviour, impulsiven...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737253/ https://www.ncbi.nlm.nih.gov/pubmed/31087031 http://dx.doi.org/10.1093/hmg/ddz100 |