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Prader–Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT(2C)R-mediated response inhibition

Prader–Willi syndrome (PWS) is a neurodevelopmental disorder caused by deletion or inactivation of paternally expressed imprinted genes on human chromosome 15q11–q13. In addition to endocrine and developmental issues, PWS presents with behavioural problems including stereotyped behaviour, impulsiven...

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Detalles Bibliográficos
Autores principales: Davies, Jennifer R, Wilkinson, Lawrence S, Isles, Anthony R, Humby, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737253/
https://www.ncbi.nlm.nih.gov/pubmed/31087031
http://dx.doi.org/10.1093/hmg/ddz100