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Acetylcholine Delays Atrial Activation to Facilitate Atrial Fibrillation

BACKGROUND: Acetylcholine (ACh) shortens action potential duration (APD) in human atria. APD shortening facilitates atrial fibrillation (AF) by reducing the wavelength for reentry. However, the influence of ACh on electrical conduction in human atria and its contribution to AF are unclear, particula...

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Detalles Bibliográficos
Autores principales: Bayer, Jason D., Boukens, Bastiaan J., Krul, Sébastien P. J., Roney, Caroline H., Driessen, Antoine H. G., Berger, Wouter R., van den Berg, Nicoline W. E., Verkerk, Arie O., Vigmond, Edward J., Coronel, Ruben, de Groot, Joris R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737394/
https://www.ncbi.nlm.nih.gov/pubmed/31551802
http://dx.doi.org/10.3389/fphys.2019.01105