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Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions
The effects of dietary zinc and L-arginine supplements on the weight gain, feed efficiency, antioxidant capacity and oxidative status of weanling piglets raised under commercial conditions were examined. A total of 288 piglets aged 21 d were fed for 15 d a diet supplemented or not with 2,500 mg/kg o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737496/ https://www.ncbi.nlm.nih.gov/pubmed/31528723 http://dx.doi.org/10.1016/j.aninu.2019.03.001 |
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author | Bergeron, Nadia Guay, Frédéric |
author_facet | Bergeron, Nadia Guay, Frédéric |
author_sort | Bergeron, Nadia |
collection | PubMed |
description | The effects of dietary zinc and L-arginine supplements on the weight gain, feed efficiency, antioxidant capacity and oxidative status of weanling piglets raised under commercial conditions were examined. A total of 288 piglets aged 21 d were fed for 15 d a diet supplemented or not with 2,500 mg/kg of zinc (provided as zinc oxide) and 1% L-arginine·HCl. The 4 treatments were distributed in a randomized complete block design with 6 initial body weight categories (12 animals per pen). Access to feed and water was ad libitum. Data were analyzed as a 2 × 2 factorial experiment using the SAS MIXED procedure, with zinc and arginine as the main independent variables. Blood collection day (d 8 and 15, samples were collected from the same 2 piglets in each pen before the morning feeding) was included as a third factor. The zinc supplement increased the average daily gain (ADG) from d 0 to 7, d 8 to 15 and d 0 to 15 (0.289 vs. 0.217 kg/d), average daily feed intake (ADFI) from d 8 to 15 and d 0 to 15 (0.338 vs. 0.279 kg/d) and the gain to feed (G:F) ratio from d 0 to 7 and d 0 to 15 (0.86 vs. 0.77) (P < 0.001). Both supplements significantly decreased the malondialdehyde concentration (zinc: 4.37 vs. 3.91 μmol/L, P = 0.005; arginine: 4.38 vs. 3.89 μmol/L, P = 0.002). Total antioxidant capacity and reduced glutathione (GSH) increased from d 8 to 15 (0.953 vs. 1.391 μmol/L, 2.22 vs. 3.37 μmol/L, P < 0.05) regardless of dietary treatment. Total and oxidized GSH concentrations on d 8 were higher in response to the combined supplements (zinc × arginine interaction, P < 0.05). Piglets fed either Zn-supplemented diet had a lower haptoglobin serum concentration (509 vs. 1,417 mg/L; P < 0.001). In conclusion, the zinc supplement improved piglet growth performance (ADG and ADFI) and oxidative status (based on malondialdehyde concentration). The arginine supplement had a limited effect on growth performance and oxidative status under these conditions. |
format | Online Article Text |
id | pubmed-6737496 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-67374962019-09-16 Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions Bergeron, Nadia Guay, Frédéric Anim Nutr Swine Nutrition The effects of dietary zinc and L-arginine supplements on the weight gain, feed efficiency, antioxidant capacity and oxidative status of weanling piglets raised under commercial conditions were examined. A total of 288 piglets aged 21 d were fed for 15 d a diet supplemented or not with 2,500 mg/kg of zinc (provided as zinc oxide) and 1% L-arginine·HCl. The 4 treatments were distributed in a randomized complete block design with 6 initial body weight categories (12 animals per pen). Access to feed and water was ad libitum. Data were analyzed as a 2 × 2 factorial experiment using the SAS MIXED procedure, with zinc and arginine as the main independent variables. Blood collection day (d 8 and 15, samples were collected from the same 2 piglets in each pen before the morning feeding) was included as a third factor. The zinc supplement increased the average daily gain (ADG) from d 0 to 7, d 8 to 15 and d 0 to 15 (0.289 vs. 0.217 kg/d), average daily feed intake (ADFI) from d 8 to 15 and d 0 to 15 (0.338 vs. 0.279 kg/d) and the gain to feed (G:F) ratio from d 0 to 7 and d 0 to 15 (0.86 vs. 0.77) (P < 0.001). Both supplements significantly decreased the malondialdehyde concentration (zinc: 4.37 vs. 3.91 μmol/L, P = 0.005; arginine: 4.38 vs. 3.89 μmol/L, P = 0.002). Total antioxidant capacity and reduced glutathione (GSH) increased from d 8 to 15 (0.953 vs. 1.391 μmol/L, 2.22 vs. 3.37 μmol/L, P < 0.05) regardless of dietary treatment. Total and oxidized GSH concentrations on d 8 were higher in response to the combined supplements (zinc × arginine interaction, P < 0.05). Piglets fed either Zn-supplemented diet had a lower haptoglobin serum concentration (509 vs. 1,417 mg/L; P < 0.001). In conclusion, the zinc supplement improved piglet growth performance (ADG and ADFI) and oxidative status (based on malondialdehyde concentration). The arginine supplement had a limited effect on growth performance and oxidative status under these conditions. KeAi Publishing 2019-09 2019-04-05 /pmc/articles/PMC6737496/ /pubmed/31528723 http://dx.doi.org/10.1016/j.aninu.2019.03.001 Text en © 2019 Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Swine Nutrition Bergeron, Nadia Guay, Frédéric Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions |
title | Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions |
title_full | Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions |
title_fullStr | Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions |
title_full_unstemmed | Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions |
title_short | Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions |
title_sort | impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions |
topic | Swine Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737496/ https://www.ncbi.nlm.nih.gov/pubmed/31528723 http://dx.doi.org/10.1016/j.aninu.2019.03.001 |
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