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Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats
The objective of this paper was to evaluate the effect of vanadium (V) in high-fat diets sourced from egg yolk on body weight gain, feed intake, blood characteristics and antioxidative status of Wistar rats. A total of 72 female Wistar rats were allocated according to a 2 × 4 factorial design throug...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737509/ https://www.ncbi.nlm.nih.gov/pubmed/31528734 http://dx.doi.org/10.1016/j.aninu.2019.05.007 |
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author | Wang, Jian-Ping Cui, Ren-Yong Ding, Xue-Mei Bai, Shi-Ping Zeng, Qiu-Feng Peng, Huan-Wei Zhang, Ke-Ying |
author_facet | Wang, Jian-Ping Cui, Ren-Yong Ding, Xue-Mei Bai, Shi-Ping Zeng, Qiu-Feng Peng, Huan-Wei Zhang, Ke-Ying |
author_sort | Wang, Jian-Ping |
collection | PubMed |
description | The objective of this paper was to evaluate the effect of vanadium (V) in high-fat diets sourced from egg yolk on body weight gain, feed intake, blood characteristics and antioxidative status of Wistar rats. A total of 72 female Wistar rats were allocated according to a 2 × 4 factorial design throughout a 5-wk trial, including 2 levels of dietary fat (normal and high; ether extract 40.3 and 301.2 g/kg; fat sourced from egg yolk) and 4 levels of dietary V (0, 3, 15 and 30 mg/kg). Vanadium decreased (P ≤ 0.05) body weight gain (V at 30mg/kg during wk 1 and 2; V at 15 and 30 mg/kg during the overall phase), feed intake (V at 30 mg/kg during wk 3 and the overall phase; V at 15 and 30 mg/kg during wk 4), but increased the relative weight of liver (V at 30 mg/kg, P ≤ 0.05). Moreover, increasing dietary V significantly increased (P ≤ 0.05) plasma aspartate aminotransferase, alanine aminotransferase and malondialdehyde levels and decreased triglyceride level, and V at 30 mg/kg in high-fat treatment had the highest or lowest values (interaction, P ≤ 0.05). Under the same dietary V dose, V residual content in liver (dietary V at 15 and 30 mg/kg) and kidney (dietary V at 15 mg/kg) was higher in high-fat diet treatment compared with normal-fat diet treatment (P ≤ 0.05). In conclusion, it is suggested that V could decrease the body weight together with the feed intake, and the high fat could enhance oxidative stress induced by V of Wistar rats. |
format | Online Article Text |
id | pubmed-6737509 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-67375092019-09-16 Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats Wang, Jian-Ping Cui, Ren-Yong Ding, Xue-Mei Bai, Shi-Ping Zeng, Qiu-Feng Peng, Huan-Wei Zhang, Ke-Ying Anim Nutr Feed Evaluation The objective of this paper was to evaluate the effect of vanadium (V) in high-fat diets sourced from egg yolk on body weight gain, feed intake, blood characteristics and antioxidative status of Wistar rats. A total of 72 female Wistar rats were allocated according to a 2 × 4 factorial design throughout a 5-wk trial, including 2 levels of dietary fat (normal and high; ether extract 40.3 and 301.2 g/kg; fat sourced from egg yolk) and 4 levels of dietary V (0, 3, 15 and 30 mg/kg). Vanadium decreased (P ≤ 0.05) body weight gain (V at 30mg/kg during wk 1 and 2; V at 15 and 30 mg/kg during the overall phase), feed intake (V at 30 mg/kg during wk 3 and the overall phase; V at 15 and 30 mg/kg during wk 4), but increased the relative weight of liver (V at 30 mg/kg, P ≤ 0.05). Moreover, increasing dietary V significantly increased (P ≤ 0.05) plasma aspartate aminotransferase, alanine aminotransferase and malondialdehyde levels and decreased triglyceride level, and V at 30 mg/kg in high-fat treatment had the highest or lowest values (interaction, P ≤ 0.05). Under the same dietary V dose, V residual content in liver (dietary V at 15 and 30 mg/kg) and kidney (dietary V at 15 mg/kg) was higher in high-fat diet treatment compared with normal-fat diet treatment (P ≤ 0.05). In conclusion, it is suggested that V could decrease the body weight together with the feed intake, and the high fat could enhance oxidative stress induced by V of Wistar rats. KeAi Publishing 2019-09 2019-07-02 /pmc/articles/PMC6737509/ /pubmed/31528734 http://dx.doi.org/10.1016/j.aninu.2019.05.007 Text en © 2019 Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Feed Evaluation Wang, Jian-Ping Cui, Ren-Yong Ding, Xue-Mei Bai, Shi-Ping Zeng, Qiu-Feng Peng, Huan-Wei Zhang, Ke-Ying Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats |
title | Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats |
title_full | Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats |
title_fullStr | Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats |
title_full_unstemmed | Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats |
title_short | Vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of Wistar rats |
title_sort | vanadium in high-fat diets sourced from egg yolk decreases growth and antioxidative status of wistar rats |
topic | Feed Evaluation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737509/ https://www.ncbi.nlm.nih.gov/pubmed/31528734 http://dx.doi.org/10.1016/j.aninu.2019.05.007 |
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