Gilteritinib: a novel FLT3 inhibitor for acute myeloid leukemia

FMS-like tyrosine kinase 3- internal tandem duplication (FLT3-ITD) remains as one of the most frequently mutated genes in acute myeloid leukemia (AML), especially in those with normal cytogenetics. The FLT3-ITD and FLT3-TKD (tyrosine kinase domain) mutations are biomarkers for high risk AML and are...

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Detalles Bibliográficos
Autores principales: Zhao, Juanjuan, Song, Yongping, Liu, Delong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737601/
https://www.ncbi.nlm.nih.gov/pubmed/31528345
http://dx.doi.org/10.1186/s40364-019-0170-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737601/
https://www.ncbi.nlm.nih.gov/pubmed/31528345
http://dx.doi.org/10.1186/s40364-019-0170-2

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