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Combined high expression of CD47 and CD68 is a novel prognostic factor for breast cancer patients

BACKGROUND: Avoiding the phagocytosis by tumor-associated macrophages (TAMs) is necessary for the growth and metastasis of solid tumors. CD47 binds to the receptor signal-regulatory protein-α (SIRP-α) on the macrophages to avoid normal phagocytosis. In this study, we evaluated the expression and pro...

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Detalles Bibliográficos
Autores principales: Yuan, Jingping, He, Huihua, Chen, Chuang, Wu, Juan, Rao, Jie, Yan, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737685/
https://www.ncbi.nlm.nih.gov/pubmed/31528120
http://dx.doi.org/10.1186/s12935-019-0957-0