The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance

BACKGROUND: Radiotherapy (RT) is a highly effective multimodal nonsurgical treatment that is essential for patients with advanced colorectal cancer (CRC). Nevertheless, cell subpopulations displaying intrinsic radioresistance survive after RT. The reactivation of their proliferation and successful c...

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Detalles Bibliográficos
Autores principales: Park, So-Yeon, Lee, Choong-Jae, Choi, Jang-Hyun, Kim, Jee-Heun, Kim, Ji-Won, Kim, Ji-Young, Nam, Jeong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737692/
https://www.ncbi.nlm.nih.gov/pubmed/31511084
http://dx.doi.org/10.1186/s13046-019-1405-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737692/
https://www.ncbi.nlm.nih.gov/pubmed/31511084
http://dx.doi.org/10.1186/s13046-019-1405-7

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