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Completing Circular Bacterial Genomes With Assembly Complexity by Using a Sampling Strategy From a Single MinION Run With Barcoding

The Oxford Nanopore MinION is an affordable and portable DNA sequencer that can produce very long reads (tens of kilobase pairs), which enable de novo bacterial genome assembly. Although many algorithms and tools have been developed for base calling, read mapping, de novo assembly, and polishing, an...

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Detalles Bibliográficos
Autores principales: Liao, Yu-Chieh, Cheng, Hung-Wei, Wu, Han-Chieh, Kuo, Shu-Chen, Lauderdale, Tsai-Ling Yang, Chen, Feng-Jui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737777/
https://www.ncbi.nlm.nih.gov/pubmed/31551994
http://dx.doi.org/10.3389/fmicb.2019.02068