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Hydroxycamptothecin Inhibits Peritendinous Adhesion via the Endoplasmic Reticulum Stress-Dependent Apoptosis

Traumatic peritendinous fibrosis is a worldwide clinical problem resulting in severe limb disability. Hydroxycamptothecin (HCPT) is an anti-neoplastic drug widely exploited in clinical practice. It has shown potential of anti-fibrosis in recent years. We previously demonstrated that HCPT inhibited t...

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Detalles Bibliográficos
Autores principales: Yao, Zhixiao, Wang, Wei, Ning, Jiexin, Zhang, Xiangqi, Zheng, Wei, Qian, Yun, Fan, Cunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737834/
https://www.ncbi.nlm.nih.gov/pubmed/31551777
http://dx.doi.org/10.3389/fphar.2019.00967