Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. At the present time, several different PBM devices are marketed to assist with hair regrowth in alopecia patients. This re...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737896/ https://www.ncbi.nlm.nih.gov/pubmed/31686888 http://dx.doi.org/10.2147/CCID.S184979 |
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author | Hamblin, Michael R |
author_facet | Hamblin, Michael R |
author_sort | Hamblin, Michael R |
collection | PubMed |
description | Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. At the present time, several different PBM devices are marketed to assist with hair regrowth in alopecia patients. This review covers the three main types of alopecia (androgenetic, areata, and chemotherapy-induced), and discusses the mechanism of action of PBM for each disease. The different devices used (mostly low powered red laser diodes), dosimetry, animal models, and clinical trials are summarized. Criteria for patient selection are outlined. Finally a perspectives section looks forward to the future. |
format | Online Article Text |
id | pubmed-6737896 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-67378962019-11-04 Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives Hamblin, Michael R Clin Cosmet Investig Dermatol Review Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. At the present time, several different PBM devices are marketed to assist with hair regrowth in alopecia patients. This review covers the three main types of alopecia (androgenetic, areata, and chemotherapy-induced), and discusses the mechanism of action of PBM for each disease. The different devices used (mostly low powered red laser diodes), dosimetry, animal models, and clinical trials are summarized. Criteria for patient selection are outlined. Finally a perspectives section looks forward to the future. Dove 2019-09-06 /pmc/articles/PMC6737896/ /pubmed/31686888 http://dx.doi.org/10.2147/CCID.S184979 Text en © 2019 Hamblin. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Hamblin, Michael R Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives |
title | Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives |
title_full | Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives |
title_fullStr | Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives |
title_full_unstemmed | Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives |
title_short | Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives |
title_sort | photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737896/ https://www.ncbi.nlm.nih.gov/pubmed/31686888 http://dx.doi.org/10.2147/CCID.S184979 |
work_keys_str_mv | AT hamblinmichaelr photobiomodulationforthemanagementofalopeciamechanismsofactionpatientselectionandperspectives |