Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives

Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. At the present time, several different PBM devices are marketed to assist with hair regrowth in alopecia patients. This re...

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Autor principal: Hamblin, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737896/
https://www.ncbi.nlm.nih.gov/pubmed/31686888
http://dx.doi.org/10.2147/CCID.S184979
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author Hamblin, Michael R
author_facet Hamblin, Michael R
author_sort Hamblin, Michael R
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description Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. At the present time, several different PBM devices are marketed to assist with hair regrowth in alopecia patients. This review covers the three main types of alopecia (androgenetic, areata, and chemotherapy-induced), and discusses the mechanism of action of PBM for each disease. The different devices used (mostly low powered red laser diodes), dosimetry, animal models, and clinical trials are summarized. Criteria for patient selection are outlined. Finally a perspectives section looks forward to the future.
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spelling pubmed-67378962019-11-04 Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives Hamblin, Michael R Clin Cosmet Investig Dermatol Review Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. At the present time, several different PBM devices are marketed to assist with hair regrowth in alopecia patients. This review covers the three main types of alopecia (androgenetic, areata, and chemotherapy-induced), and discusses the mechanism of action of PBM for each disease. The different devices used (mostly low powered red laser diodes), dosimetry, animal models, and clinical trials are summarized. Criteria for patient selection are outlined. Finally a perspectives section looks forward to the future. Dove 2019-09-06 /pmc/articles/PMC6737896/ /pubmed/31686888 http://dx.doi.org/10.2147/CCID.S184979 Text en © 2019 Hamblin. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Hamblin, Michael R
Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
title Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
title_full Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
title_fullStr Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
title_full_unstemmed Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
title_short Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
title_sort photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737896/
https://www.ncbi.nlm.nih.gov/pubmed/31686888
http://dx.doi.org/10.2147/CCID.S184979
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