Glutamine independence is a selectable feature of pluripotent stem cells

Most rapidly proliferating mammalian cells rely on the oxidation of exogenous glutamine to support cell proliferation. We previously found that culture of mouse embryonic stem cells (ESCs) in the presence of inhibitors against MEK and GSK3β to maintain pluripotency reduces cellular reliance on gluta...

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Detalles Bibliográficos
Autores principales: Vardhana, Santosha A., Arnold, Paige K., Rosen, Bess P., Chen, Yanyang, Carey, Bryce W., Huangfu, Danwei, Carmona-Fontaine, Carlos, Thompson, Craig B., Finley, Lydia W.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737941/
https://www.ncbi.nlm.nih.gov/pubmed/31511848
http://dx.doi.org/10.1038/s42255-019-0082-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737941/
https://www.ncbi.nlm.nih.gov/pubmed/31511848
http://dx.doi.org/10.1038/s42255-019-0082-3

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