Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model

Amyotrophic lateral sclerosis (ALS) presents a poorly understood pathogenesis. Evidence from patients and mutant SOD1 mouse models suggests vascular damage may precede or aggravate motor dysfunction in ALS. We have previously shown angiogenin (ANG) treatment enhances motor neuron survival, delays mo...

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Detalles Bibliográficos
Autores principales: Crivello, Martin, Hogg, Marion C., Jirström, Elisabeth, Halang, Luise, Woods, Ina, Rayner, Megan, Coughlan, Karen S., Lewandowski, Sebastian A., Prehn, Jochen H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737946/
https://www.ncbi.nlm.nih.gov/pubmed/31383794
http://dx.doi.org/10.1242/dmm.040238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737946/
https://www.ncbi.nlm.nih.gov/pubmed/31383794
http://dx.doi.org/10.1242/dmm.040238

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