C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells

Amyotrophic lateral sclerosis (ALS) is a late-onset neuromuscular disease with no cure and limited treatment options. Patients experience a gradual paralysis leading to death from respiratory complications on average only 2-5 years after diagnosis. There is increasing evidence that skeletal muscle i...

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Detalles Bibliográficos
Autores principales: Lynch, Eileen, Semrad, Theran, Belsito, Vincent S., FitzGibbons, Claire, Reilly, Megan, Hayakawa, Koji, Suzuki, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737948/
https://www.ncbi.nlm.nih.gov/pubmed/31439573
http://dx.doi.org/10.1242/dmm.039552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737948/
https://www.ncbi.nlm.nih.gov/pubmed/31439573
http://dx.doi.org/10.1242/dmm.039552

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